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Health Management and Education

Health Management and Education

Other injectable medications for diabetes

 

Pramlintide (Symlin)

Drug Name  Brand Name  Doses Available (mcg) 
Pramlintide Symlin 15-120

This medication is a member of the synthetic amylin (neuroendocrine hormone) class.

How it works

  • This medication is used with insulin to lower blood sugar, especially after meals by slowing down the rate in which food is digested
  • Decreases glucose secretion by the liver
  • Works to decrease appetite, some people may lose weight as a result

Guidelines for useSymlin pens

  • In people with Type 1 diabetes using insulin
  • In people with Type 2 diabetes who are taking insulin, Sulfonylurea and/or Metformin

What to do if a dose is forgotten

  • Resume usual dose at next scheduled injection time
  • Do not “double up” on Symlin

Side effects

Side effects may occur when starting this medication but will often lessen once your body is used to the medication

  • Nausea, vomiting, diarrhea, headache
  • May cause severe low blood sugars if pre-meal insulin dose not adjusted

Who should NOT take this medication

  • People with Type 2 diabetes who are on not insulin
  • People with digestive issues (gastroporesis)

 

Exenatide (Byetta)

Drug Name  Brand Name  Doses Available (mcg) 
Exenatide Byetta 5, 10

This medication is the member of incretin mimetic class.

How it worksByetta pens

  • Increases glucose dependent insulin secretion
  • Decreases output of sugar by the liver
  • Decreases the rate sugar enters blood by delaying how the food is digested in the gut
  • Decreases food intake by appetite suppression, some people may lose weight as a result

Guidelines for use

  • Byetta is indicated as add-on therapy to improve blood sugar control in people with Type 2 diabetes who are taking Metformin, a Sulfonylurea, a Thiazolidinedione, or a combination of these medications
  • Inject 30-60 minutes before breakfast and dinner

What to do if a dose is forgotten

  • Resume usual dose at next scheduled injection time
  • Do not “double up” on Byetta

Side effects

Side effects may occur when starting this medication but will often lessen once your body is used to the medication

  • Nausea, vomiting, diarrhea, jitters, dizziness, headache
  • If you arte taking a Sulfonylurea with Byetta, you may experience a low blood sugar

Who should NOT take this medication

  • People with Type 1 diabetes or people with severe kidney problems or digestive issues (gastroporesis)