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Department of Internal Medicine

Department of Internal Medicine

Current Research

Dr. Weiss's Lab

Robert H. Weiss's Lab

We have several projects in the laboratory all relating to kidney disease and cancer. Our laboratory is uniquely situated to study the intersection between intrinsic renal disease and cancer, and is likely one of the few laboratories in this position. We have collaborations both nationally and internationally. Projects in the laboratory include but are not limited to:

  • Metabolomics and proteomics analysis of kidney cancer and ADPKD for biomarker and therapeutic target discovery
  • The role of the tumor suppressor proteins and p21 in renal cancer and ADPKD
  • Validation of nuclear transport inhibitors and PPAR-alpha as potential cancer and kidney disease therapeutics
  • Study of the tryptophan and glutamine metabolic pathways in kidney cancer
  • Glycomics analysis of IgA nephropathy
  • The mechanism of increased renal tumorigenesis in chronic kidney disease
  • Grade dependent mechanisms and potential therapies in kidney cancer

Lab Publications Lab Publications

Dr. Weiss & Lab Personnel Information

Robert H. Weiss, MD

Robert H. Weiss, MD
Email: rhweiss@ucdavis.edu
Phone: (530) 752-3341

Education:
University of California, Santa Cruz, CA, BA, 1976
University of California, Los Angeles, CA, MS, Physical Chemistry, 1976
University of California, Los Angeles, CA, MS, Medical Physics, 1980
University of California, Irvine, CA, MD, 1984
California Pacific Medical Center, Residency, Internal Medicine, 1987
University of California, San Francisco, CA, Fellowship, Nephrology, 1991

Employment:
University of California, Davis, School of Medicine, Professor of Medicine, Current
Mather (Sacramento) VAMC, Sacramento, CA, Chief, Nephrology Section, Current

Omran Abu Aboud, Ph.D.

Omran Abu Aboud, Ph.D.
Email: oaabuaboud@ucdavis.edu
Phone: (530) 752-8868

Education:
Alfateh University, Tripoli Libya, DVM, 1995
Ghent University, Gent Belgium, MS, 2005
University of California, Davis, CA, MPVM, PhD, 2009-Present

Employment:
University of Tripoli, Tripoli, Libya, Ved Med Student, 1989-1995
University of Tripoli, Tripoli, Libya, TA & Veterinarian, 1996-2001
University of Gent, Gent Belgium, Grad Student, 2002-2005
University of Tripoli, Tripoli, Libya, Professor, 2006-2008
University of California, Davis, ESL Student, 2008-2009
University of California, Davis, Grad Student, Current Position

Publications: Omran Abu Aboud Publications

Justin Van Hoorebeke

Justin Van Hoorebeke
Email: jsvanhoorebeke@ucdavis.edu
Phone: (530) 752-8868

Education:
University of California, Davis, BS, 2012
University of California, Davis, MS, 2015

Employment:
University of California, Fresno, CA, Academic Research Associate, 2008-2009
University of California, Davis, CA, Teaching Asssistant, Current Position 

Matthew Tan

Matthew Tan
Email: mattan@ucdavis.edu
Phone: (530) 752-8868

Education:
University of California, Davis, CA, BS, 2009
University of California, Davis, CA, MS, Current

Employment: 
University of California, Davis, CA, Graduate Teacher Assistant, 2011-Current
Davis Community Clinic, Davis, CA, Shadow Physician Assistant, 2012-Current
Onsite Medical Service, Davis, CA, Emergency Medical Technician, 2012-Current
University of California, Davis, CA, Grad Student, Current Position

Current Research Projects:

  • Inhibition of CRM1 to reduce cystic growth in polycystic kidney disease.

Josie Trott, Ph.D.

Josephine Trott, Ph.D.
Email: jftrott@ucdavis.edu
Phone: (530) 752-8868

Education:
B.Sc.Agr, Agricultural Genetics, University of Sydney, Australia, 1995
PhD Zoology and Molecular Biology,  Department of Zoology, University of Melbourne, Australia  1999

Employment:
Postdoctoral Fellow: National Cancer Institute, NIH, Bethesda, MD USA 1999-2001
Postdoctoral Associate: Department of Animal Science, University of Vermont, VT, USA 2002-2005
Research Associate: Department of Animal Science, University of Vermont, VT, USA 2005-2007
Assistant Project Scientist: Department of Animal Science, UC Davis, CA, USA 2008-2013
Associate Project Scientist: Department of Animal Science and Division of Nephrology, UC Davis, CA, USA. Current Position

Current Research Projects:

  • Investigating the role of tryptophan metabolism in renal cell carcinoma
  • Elucidation of the enzymes involved in glutamine metabolism in renal cell carcinoma with the view to using enzyme inhibitors to decrease cancer cell proliferation

Publications: Josie Trott's Pubs

Hiromi Inoue Wettersten, Ph.D.

Hiromi Inoue Wettersten, Ph.D.
Email: inoue@ucdavis.edu
Phone: (530) 752-8868

Education:
Tottori University, Tottori, Japan, DVM, 2007
University of California, Davis, MPVM, 2009
University of California, Davis, PhD, 2012

Employment:
University of California, Davis, GSR, Current Position

Current Research Projects:

  • Efficacy of CRM1 inhibitors in renal cell carcinoma and polycystic kidney disease
  • Role of glutamine metabolism in renal cell carcinoma in patients with chronic kidney disease
  • Energy metabolism in renal cell carcinoma
  • Role of p21 in renal cell carcinoma


Publications: Hiromi Inoue Wettersten Pubs

Arzu Ulu, Ph.D.

Arzu Ulu, Ph.D.
Email: aulu@ucdavis.edu
Phone: (530) 752-8868

Education: 
Ankara University, Turkey, BS, 2001
Ankara University, Turkey, M.Sc., 2004
Ankara University, Turkey, Ph.D., 2006
University of California, Davis, Ph.D., 2013

Employment: 
Ankara University, Turkey, Research Assistant, 2002-2006
University of California, Davis, Junior Specialist, 2006-2007
University of California, Davis, Postdoctoral Scholar, 2013-Current Position
 
Publications: Publications

Lab Address

451 Health Sciences Drive
GBSF 6310 - 6th Floor
Davis, CA 95616 (map it)
(530) 752-3341