Clinical/Research Interests

Providing highly specialized consultations in the diagnosis and treatment of complex unexplained neurological abnormalities affecting visual pathways. The typical case is a patient who experiences unexplained vision loss. Routine diagnostic tests and a thorough evaluation by an ophthalmologist and/or neurologist and other appropriate sub specialists. Less complicated cases can often be resolved with a telephone consultation.

Facilitating the service's hallmark diagnostic capabilities is a full complement of the most sophisticated diagnostic tools and technology, including computerized visual field testing, the latest in 3-D digital imaging and electrophysiological testing, including VEP, ERG MFVEP and MFERG.

The department's neuro-ophthalmology service accepts referrals statewide, nationally and internationally from ophthalmologists, neurologists, neurosurgeons and other physician specialists.

Research:

Dr. Keltner directs the Visual Field Reading Center for both the Longitudinal Optic Neuritis Study and Ocular Hypertension Treatment Study. He is the Co-Director of the OCT Reading Center with Dr Jack Werner He is an internationally known neuro-ophthalmologist who treats a wide variety of conditions. His areas of research interest include the use of botulinum toxin for the treatment of facial spasms, effects of cancer on the eye, autoimmune-related retinopathies, optic neuropathies that affect vision and automated visual field testing.

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Select Recent Publications:

Choi SS, Zawadzki RJ, Keltner JL, Werner JS. Changes in cellular structures revealed by ultra-high resolution retinal imaging in optic neuropathies. Investigative Ophthalmology & Visual Science, 49(5):2103-2119. 2008.

Choi SS, Zawadzki RJ, Greiner MA, Keltner JL, Werner JS. Fourier-domain optical coherence tomography and adaptive optics reveal nerve fiber layer loss and photoreceptor changes in a patient with optic nerve drusen. Journal of Neuro-Ophthalmology, 28(2):120-125.2008.

Sanchez R, Smith A, Carelli V, Sadun A, Keltner JL. Leber Hereditary Optic Neuropathy Possible Triggered by Exposure to Tire Fire. Journal of Neuro-Ophthalmology, 26(4), 268-272. Helped collect data and write manuscript. 2007.

Keltner JL, Fine SL, Abrams GW and Mondino B. Subspecialty Fellowships: Standardizing and Enchancing the Educational Experience. Ophthalmology, 144(4): 628. 2007.

Gerth C, Zawadzki RJ, Choi SS, Keltner JL, Park SS, Werner JS. Visualization of lipofuscin accumulation in Stargardt macular dystrophy by high-resolution Fourier-domain optical coherence tomography. Archives of Ophthalmology, 125(4):575. 2007.

Levine RA, Demirel S, Fan J, Keltner JL, Johnson CA, Kass MA, and the Ocular Hypertension Treatment Study Group "Asymmetries and Visual Field Summaries as Predictors of Glaucoma in the OHTS." Invest Ophthalmology & Visual Science, 47(9): 3896-3903. Part of the OHTSG. 2006.

Keltner JL, Johnson CA, Anderson DR, Levine RA, Fan J, Cello KE, Quigley HA, Budenz DL, Parrish RK, Kass MA, Gordon MO and the Ocular Hypertension Treatment Study Group. The Association Between Glaucomatous Visual Fields and Optic Nerve Head Features in the Ocular Hypertension Treatment Study (OHTS). Ophthalmology, 113(9):1603-1612. Part of the OHTSG. 2006.

Levine RA, Demirel S, Fan J, Keltner JL, Johnson CA, Kass MA, and the Ocular Hypertension Treatment Study Group "Asymmetries and Visual Field Summaries as Predictors of Glaucoma in the OHTS." Invest Ophthalmology & Visual Science, 47(9): 3896-3903. Part of the OHTSG. 2006.

Keltner, JL, Thirkill CE, Yip PT. Clinical and Immunologic Characteristics of Melanoma-Associated Retinopathy Syndrome: Eleven New Cases and a Review of 51 Previously Published Cases. J. Neuro-Ophthalmology 21(3):173-187. 2001

Keltner JL, Johnson CA, Quigg JM, Cello KE, Kass MA, Gordon MO, Spurr JO and the Ocular Hypertension Study Group. Confirmation of Visual Field Abnormalities in the Ocular Hypertension Treatment Study (OHTS) Arch Ophthalmol 118. 2000