Department of Dermatology

Department of Dermatology

Maverakis Laboratory Publications

Most relevant to our current research

  1. Maverakis E, Beech JT, Wilson SS, Quinn A, Pedersen B, and Sercarz EE. T cell receptor CDR3-length analysis reveals the absence of a characteristic public T cell repertoire in neonatal tolerance: the response in the "tolerant" mouse within the residual repertoire is quantitatively similar but qualitatively different. THE JOURNAL OF EXPERIMENTAL MEDICINE 191: (4) 695-702 FEB 2000.
  2. Maverakis E, Beech J, Stevens DB, et al. Autoreactive T cells can be protected from tolerance induction through competition by flanking determinants for access to class II MHC. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES U.S.A 100 (9): 5342-5347 APR 29 2003.
  3. Menezes JS, van den Elzen P, Thornes J, Huffman D, Droin N, Maverakis E, and Sercarz EE. Despite clonal dominance by discrete T cell populations which appear as public clonotypes during EAE induction, the entire available repertoire is heterogeneous. JOURNAL OF CLINICAL INVESTIGATION 117(8):2176-85 2007.
  4. Maverakis E*, Menezes J, Ametani A, Han M, Stevens DB, He Y, Lam KS, Ward ES and Sercarz EE. Mimics induce a non-autoaggressive repertoire which preempts induction of autoimmunity. (*EM corresponding author). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES U.S.A 2010 9;107(6):2550-5.
  5. Takada Y, Sagusa J, Mitsiades C, Mitsiades N, Tsai J, He Y, Maningding E, Coleman A, Maverakis D, Rodriquez R, Takada Y and Maverakis E. A T Cell-binding fragment of fibrinogen can prevent autoimmunity. In Press JOURNAL OF AUTOIMMUNITY

Other recent publications of importance

(selected from 24 accepted PubMed indexed manuscripts)

  1. Maverakis E, Mendoza R, Campagnoni AT, Southwood S. Sette A, Abromson-Leeman S and Sercarz EE. Immunogenecity of self antigens is unrelated to MHC-binding affinity: T Cell Determinant Structure of Golli MBP in the BALB/c Mouse. JOURNAL OF AUTOIMMUNITY 15: (3) 315-322 NOV 2000.
  2. Abromson-Leeman S, Maverakis E, Bronson R, et al. CD40-mediated activation of T cells accelerates, but is not required for, encephalitogenic potential of myelin basic protein-recognizing T cells in a model of progressive experimental autoimmune encephalomyelitis. EUROPEAN JOURNAL OF IMMUNOLOGY 31 (2): 527-538 FEB 2001.
  3. Maverakis E, van den Elzen P, Sercarz EE. Self-reactive T cells and degeneracy of T cell recognition: Evolving concepts - from sequence homology to shape mimicry and TCR flexibility JOURNAL OF AUTOIMMUNITY 16 (3): 201-209 MAY 2001.
  4. Sercarz EE, Maverakis E MHC-guided processing: Binding of large antigen fragments. NATURE REVIEWS IMMUNOLOGY 3 (8): 621-629 AUG 2003
  5. Robinson WH, Fontoura P, Lee BJ, de Vegvar HEN, Tom J, Pedotti R, DiGennaro CD, Mitchell DJ, Fong D, Ho PPK, Ruiz PJ, Maverakis E, Stevens DB, Bernard CCA, Martin R, Kuchroo VK, van Noort JM, Genain CP, Amor S, Olsson T, Utz PJ, Garren H, Steinman L. Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis. NATURE BIOTECHNOLOGY 21 (9): 1033-1039 SEP 2003
  6. Elewaut D, Lawton AP, Nagarajan NA, Maverakis E, Khurana A, Honing S, Benedict CA, Sercarz E, Bakke O, Kronenberg M, Prigozy TI. The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of V alpha 14i NKT cells JOURNAL OF EXPERIMENTAL MEDICINE 198 (8): 1133-1146 OCT 20 2003
  7. Wadhera A, Maverakis E, Mitsiades N, et al., Thymoma Associated Multiorgan Autoimmunity: A GVHD-Like Disease. JOURNAL AMERICAN ACADEMY OF DERMATOLOGY: April 12, 2007.
  8. Maverakis E*, Beech, JT, Schneider S, and Sercarz EE. Presentation of a determinant by MHC class II can be prevented through competitive capture by a flanking determinant on a multideterminant peptide. (*EM corresponding author) JOURNAL OF AUTOIMMUNITY Aug;31 2008
  9. Chen HY, Fermin A, Vardhana S, Weng IC, Lo KF, Chang EY, Maverakis E, Yang RY, Hsu D, Michael Dustin M, Liu FT. Galectin-3 negatively regulates TCR-mediated CD4+ T cell activation at the immunological Synapse. In Press PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES U.S.A.
  10. Maverakis E, Miyamura Y, Bowen MP, Correa G, Ono Y, Goodarzi H. Light including ultraviolet. In Press JOURNAL OF AUTOIMMUNITY Dec 15 2009 [Epub ahead of print]
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