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Clinical and Translational Science Center

Clinical and Translational Science Center

Describing the CTSC in a Grant Application


 Remember to get quotes for services in advance of submission

The CTSC provides key services to investigators, trainees, and staff to facilitate clinical and translational research. Investigators who wish to include CTSC services and programs in their grant applications may use the following descriptive language. It is important to ensure that the costs of any services needed are obtained in advance of application for your research are included in the budget submitted. The best way to obtain the necessary information for submitted budgets and budget justifications are through a Request for Services application or you can contact individual program managers for additional information. Investigators will need a Kerberos ID and provide some basic information in order to process the request.

  • UC Davis Clinical and Translational Science Center (CTSC)
    The UC Davis CTSC was established in October 2006 with a $24.8 million Clinical and Translational Science Award from the NIH. The CTSC, now one of 61 NIH-supported centers nationally, is focused on enhancing the study of human health and disease, and bringing new treatments more rapidly to patients and communities (www.ucdmc.ucdavis.edu/ctsc/). The CTSC, physically housed in a specially renovated 16,000 sq. ft. facility on the Sacramento campus, draws talent and leadership from departments and divisions across the Davis and Sacramento campuses as well as community and institutional partners in the region. The CTSC is an academic home for innovative and collaborative research across the UC Davis campus, and a part of a national consortium bridging basic, translational, and clinical research using a transformative approach. The consortium is designed to: (1) encourage the development of new methods and techniques to enhance clinical and translational research, (2) improve training and mentoring to ensure that new investigators are educated in the conduct of clinical and translational research, (3) enhance the ability of investigators to navigate the increasingly complex research system, (4) design new and improved clinical research informatics tools, (5) assemble multidisciplinary teams that cover the spectrum of clinical and translational research, and (6) forge new partnerships with private and public entities that will help transform the clinical enterprise. A key feature of the UC Davis CTSC is an education program focused on "team science" and an extensive collaborative culture across UC Davis schools, colleges, and centers. The UC Davis CTSC has implemented several programs to enhance communication, encourage sharing, facilitate research, and train multidisciplinary teams that will conduct clinical and translational research in the future. Key programs in the CTSC include the following:  Biomedical Informatics; Research Education, Training, and Career Development ; Translational Technologies, Methodologies, and Resources;  Pilot Translational and Clinical Studies; Research Design, Biostatistics, and Clinical Research Ethics; Regulatory Support; the Clinical Research Center; and Community Engagement. Through these programs the UC Davis CTSC transforms research and aids in supporting and facilitating new collaborative scientific discoveries that will bring new techniques and therapies into medical practice, and help to solve complex medical problems.
  • Research Education, Training and Career Development
    The goal of this program is to create a cadre of multidisciplinary clinical and translational researchers through effective research education, training, and career development. Trainees and junior faculty acquire state-of-the-art multidisciplinary skills in clinical and translational research through three training mechanisms: an innovative T32 pre-doctoral program in “team science” for medical and graduate students; an enhanced K30 Mentored Clinical Research Training Program for junior faculty; and a K12 Mentored Career Development Program for junior faculty. These training programs are also highly integrated with several other UC Davis training programs in translational research  including the NIH-funded Building Interdisciplinary Research Careers in Women's Health (BIRCWH) program; the Howard Hughes Medical Institute (HHMI)-funded Integrating Medicine into Basic Science Program; the UC Davis Stem Cell Training Program supported by the California Institute for Regenerative Medicine (CIRM); the Agency for Healthcare Research and Quality (AHRQ) Primary Care Outcomes Research (PCOR) training program; and NIH-supported K12 programs in Emergency Medicine and Oncology.
  • Pilot Translational and Clinical Studies
    The Pilot Translational and Clinical Studies program aims to spark innovative and collaborative scientific endeavors by supporting and facilitating robust new research paradigms, technologies, and tools, and through partnerships that enhance team science. The CTSC has circulated calls throughout the campus community for applications on targeted topics, and has maximized and leveraged opportunities throughout UC Davis including other NIH-supported centers and programs. All funded investigators and the titles of their projects are listed on the CTSC website to highlight their success and innovation. identification of transformative outcomes. In addition, potential new research opportunities are noted and, where appropriate, investigators are directed to the Translational Technologies, Methodologies, and Resources program to determine potential commercialization of their work.
  • Translational Technologies, Methodologies, and Resources
    The overriding objective of the Translational Technologies, Methodologies, and Resources program is to serve as a facilitator, encourage investigators to form multidisciplinary partnerships, and link investigators with the resources needed to undertake novel studies. To implement these objectives, the program provides ready access to core services and facilities through the Facilities, Cores, and Resources website, organizes collaborative workshops and symposia on key thematic areas that are frequently associated with calls for pilot project applications, and supports local and national translational research initiatives.
  • Community Engagement
    The Community Engagement program is a major resource linking investigators and community partners. The program is focused on implementing the CTSC mission of building capacity and infrastructure for clinical and translational research among investigators, health care providers, and community-based organizations. Partners include California health agencies and elected officials around health and healthcare issues. The CTSC has built capacity for community-engaged research and includes a research agenda responsive to community priorities by implementing a Research and Education Community Advisory Board and a consultation service that is aimed at investigators that conduct practice-based research, and at community members seeking academic research expertise.
  • Biomedical Informatics
    The Biomedical Informatics team helps develop strategies to manage clinical and translational research data and maintains a registry of volunteers. Programmers are available to assist investigators with database design and management, secure data sharing, and electronic data capture. In addition, there is expertise available to help develop data specifications and consistent terminology, extract cohorts of de-identified data to establish study feasibility, provide cohorts of potential study candidates from electronic medical records and aggregate databases, and assist in preparation of a data set for statistical analysis. Through the Biomedical Informatics program, researchers have access to Volunteer Registry, SciVal, Cohort Discovery, REDCap, Velos, and Data Explorer.
  • Research Design, Biostatistics, and Clinical Research Ethics
    The Design, Biostatistics, and Clinical Research Ethics program strengthens research plans through study design, analysis, and consultation. Expertise is available to help develop protocols, statistical plans, data safety monitoring plans, data analysis, and contribute to the statistical sections of grant applications, abstracts, and manuscripts.  
  • Clinical Research Center
    The CTSC Clinical Research Center (CCRC) is a main component of the Clinical Research Resources and Facilities program. The CCRC has an outpatient clinic on the UC Davis Medical Center campus and provides in/outpatient services at the VA Northern California Health Care System. The in/outpatient clinic  is an 8,000 sq. ft., nine-bed unit that provides clinical research facilities and patient-oriented resources and services, including nursing, nutrition, phlebotomy, laboratory, and physiological assessment components. Resources for patient-oriented research, as well as flexible, mobile research personnel are available for investigators and staff. The CCRC has collaborative research relationships with the Western Human Nutrition Research Center on the Davis campus, the M.I.N.D. Institute, Shriner’s Hospital for Children Northern California, and the UC Davis Comprehensive Cancer Center. The CCRC is able to provide continuous 24 hours/day, 7 days/week support for inpatient and outpatient protocols.
  • Regulatory Knowledge and Support
    The Regulatory Knowledge and Support program provides assistance to investigators, scholars, and staff with the regulations and best practices that guide clinical research. The Clinical Trial Resource Group facilitates compliance with Good Clinical Practice, local, state, and federal regulations (e.g.,IRB, HIPAA, Informed Consent, and FDA), Medicare and private payer cost analysis, budgeting and billing, and resources to help monitor, mentor, and foster quality assurance. The Program leads SoCRA certified training opportunities including a diverse range of topics and provides a Coordinator Training Program,  Informed consent “Bootcamp,” and “Navigating the Clinical Trials Administrative Process.”