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Clinical and Translational Science Center

Clinical and Translational Science Center

Center for Reducing Health Disparities

Resource List - Cancer Disparities Research

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Asian Americans and Cancer Clinical Trials. A Mixed-Methods Approach to Understanding Awareness and Experience 
(UCD Authors)
Barriers to recruitment of minority populations affect the generalizability and impact of clinical trial findings for those populations.  A survey was administered to new cancer patients.  Comparison of survey results for Asian-American respondents and non-Asian respondents indicated that Asians were less likely to have heard the term “clinical trial” and were more likely to define a clinical trial as “an experiment” or “a test procedure in a clinic” than non-Asians.  Multiple strategies will be necessary to enhance awareness of and experience with accrual to cancer clinical trials for Asians.

Overcoming Barriers to Cancer Clinical Trial Accrual. Impact of Mass Media Campaign. 
(UCD Authors)
The object of this study was to increase awareness of cancer clinical trials and SB 37 through a mass multi-media campaign.  Awareness level predicted willingness to participate.  Blacks, Asians, and lowest income groups were the least willing to participate.  Awareness increased significantly at UCD versus the UCSD cohort.  It was unclear whether this increase was attributable entirely to the multi-media campaign or to varying demographic variables.

Persistent Racial and Ethnic Disparities in Up-to-Date Colorectal Cancer Testing in Medicare Enrollees. 
(UCD Authors)
The object of this study was to assess whether there is greater colonoscopy use among white as compared with nonwhite Medicare enrollees since Medicare established coverage for colorectal cancer screening has been associated with a widening in white versus nonwhite disparities in up-to-date colorectal cancer screening testing status.  Although white versus nonwhite disparities in up-to-date status via colonoscopy widened, this was counterbalanced by narrowing white versus nonwhite disparities in up-to-date status via fecal occult blood test and sigmoidoscopy.

Trends in Colorectal Cancer Testing Among Medicare Subpopulations.
(UCD Authors)
In 1998, Medicare initiated universal coverage for colorectal cancer screening via fecal occult blood testing and sigmoidoscopy. In mid-2001, universal coverage was advanced to screening colonoscopy. This study sought to determine whether trends in colorectal cancer testing differed among racial/ethnic, age, or gender subgroups of the Medicare population.  The study found that colonoscopy is supplanting sigmoidoscopy as a colorectal cancer test among Medicare enrollees, while fecal occult blood testing use is in decline. The transition from sigmoidoscopy to colonoscopy has occurred more quickly among white than nonwhite Medicare enrollees.

Determinants of Racial/Ethnic Colorectal Cancer Screening Disparities. 
(UCD Authors)
This study found that determinants of racial/ethnic colorectal cancer screening disparities vary among minority groups, suggesting the need for different interventions to mitigate those disparities.  Whereas socioeconomic, access, and language barriers seem to drive the colorectal cancer screening disparities experienced by blacks and Hispanics, additional factors may exacerbate the disparities experienced by Asians.

Factors Associated with Hispanic/non-Hispanic White Colorectal Cancer Screening Disparities. 
(UCD Authors)
In the United States, Hispanics are less likely to undergo colorectal cancer (CRC) screening than non-Hispanic whites (whites).  Factors associated with CRC screening disparities between Hispanics and non-Hispanic whites appear similar among Hispanic sub-groups. However, the relative contribution of these factors to disparities varies by Hispanic national origin group, suggesting a need for differing approaches to increasing screening for each group (Mexican, Cuban, Puerto Rican, or Dominican).

Can Patient Coaching Reduce Racial/Ethnic Disparities in Cancer Pain Control? Secondary Analysis of a Randomized Control Trial. 
(UCD Authors)
Minority patients with cancer experience worse control of their pain than do their white counterparts. This disparity may reflect more miscommunication between minority patients and their physicians. Therefore, we examined whether patient coaching could reduce disparities in pain control in a secondary analysis of a randomized controlled trial.  At enrollment, minority patients had significantly more pain than their white counterparts.  At follow-up, minorities in the control group continued to have more pain, whereas in the experimental group, disparities were eliminated.  The effect of the intervention on reducing disparities was significant.  Patient coaching offers promise as a means of reducing racial/ethnic disparities in pain control. Larger studies are needed to validate these findings and to explore possible mechanisms.

Trends in Prostate Cancer Mortality among Black Men and White Men in the United StatesUsing prostate cancer incidence, survival, and incidence-based mortality rates from the Surveillance, Epidemiology, and End Results (SEER) Program for the U.S. population, this study investigates the mechanism for declining prostate cancer mortality rates in the US.  Prostate cancer mortality rates declined sharply after 1991 for white men and after 1992 for black men.  The age adjusted mortality rates have dropped below the rate in 1986 since 1995 for white men and 1997 for black men.  This decrease reflects the increased use of prostate specific antigen testing which began in 1986.