Highly skilled clinical research nurses implement protocol-specific procedures and provide direct nursing care for all subjects enrolled in research studies. The nurses' areas of expertise vary to accommodate a wide spectrum of clinical research strategies and disciplines. All staff are trained annually in GCP and monitor for GCP compliance with each study they are assigned. All CTSC Clinical Research Center nurses meet strict hospital and unit-based competencies, and are ACLS/PALS, conscious sedation, and chemotherapy certified. A Nurse Practitioner is available to provide expanded services to investigators.For more information, please contact: Nicole Mullen, RN, MSN
An Exercise Physiologist is available to provide investigators the following services: Measuring and analyzing DEXA scans (Total Body, Spine and Hip); measuring total body water and body composition using BIS; measuring basal and resting metabolic rate, monitoring physical activity using accelerometers; measuring various circumference sites; performing V02 maximal effort tests on an exercise bike and treadmill, monitoring heart rate and blood pressure and calculating follow-up exercise protocols based on Maximal Heart Rate reserves; measuring body composition using the Bod Pod; maintaining a pedometer log database; administering 7-day physical activity recall questionnaires; calculating energy expenditure; providing exercise guidance; performing manual muscle testing; hand held dynometry; and spirometry testing to determine lung capacity; administering quality of life questionnaires; and analyzing and managing all data collected.The following equipment are available to investigators:
- BOD POD: The BOD POD provides a measurement of air displacement that is used to determine body density and body fat. It can be used with individuals weighing up to 400 pounds.
- DEXA: Dual energy X-ray absorptiometry (DEXA) is used for assessment of bone density and body composition (body fat and lean mass).
- Metabolic Cart: The ParvoMedics metabolic cart measures metabolism at rest and during exercise and it meaures the thermic effect of food on metabolism using a controlled diet.
- Bio-electrical Impedance: A noninvasive method used for determining total body water, as well as changes in body composition specifically, fat free mass, fat mass and total body fat.
- 12 Lead EKG Stress System: The Quinton Q-Stress System directly interfaces with the Quinton TM55 treadmill for research requiring cardiac exercise testing
- Activity and heart rate monitors: Polar 810i heart rate monitors and Actigraph GT1M accelerometers are used to measure heart rate, activity, and energy expenditure in the lab or in the field.
A Research Dietitian is available to provide investigators the following services: nutritional status assessments; food record processing and analysis; nutritional education/counseling to optimize health status and research protocol adherence; metabolic and calorie-controlled meal planning and preparation; and protocol planning/consultations.For more information, please contact: Christine Feller, Ph.D.
Highly skilled laboratory staff support investigators with all laboratory assistance including sample processing; preparing aliquots of samples; sample storage; DNA/RNA isolation; preparation of samples for proteomics and flow cytometry; and multiplex cytokine/chemokine and metabolic analyses. VA and UCD clinical lab services are also available to investigators.For more information, please contact: Joshua W. Miller, Ph.D.
The VA's Department of Radiology provides CCRC investigators with general radiology, imaging, and nuclear medicine imaging services. Special research rates are applied to CCRC studies; however, a service contract for reimbursement is required before imaging services are provided.For more information, please contact: Lisa A. Wilson
A Clinical Research Coordinator provides supplemental regulatory and study visit support to CCRC investigators and serves as a primary resource for clinical research coordinators accessing CCRC support.For more information, please contact: Lisa A. Wilson
Education and Training
Educational and training opportunities are available to any member of the research team, including student nurses, new clinical research nurses, research coordinators, dietetic interns, new phlebotomists, medical residents, and fellows.For more information, please contact: Nicole Mullen, RN, MSN