Associate Professor 
Biochemistry and Molecular Medicine (SOM)
UC Davis Medical Center Research I Room 3002
(916) 734-3656
shlo@ucdavis.edu

Ph.D. - Harvard University - Cell and Developmental Biology - 1993
BS - National Taiwan University - 1986

Cell-cell and cell-matrix junctions, focal adhesions, cytoskeleton, signal transduction, tensin, animal models for human diseases.

• Cell and Developmental Biology 
• Pharmacology and Toxicology
• Biochemistry and Molecular Biology
• Comparative Pathology

• Menachem Katz, Ido Amit, Ami Citri, Tal Shay, Silvia Carvalho, Sara Lavi, Fernanda Milanezi, Ljuba Lyass, Ninette Amariglio, Jasmine Jacob-Hirsch, Nir Ben-Chetrit, Gabi Tarcic, Moshit Lindzen, Roi Avraham,Yi-Chun Liao, Patricia Trusk, Asya Lyass, Gideon Rechavi, Neil L. Spector, Su Hao Lo, Fernando Schmitt, Sarah S. Bacus, Yosef Yarden
  A reciprocal tensin-3-cten switch mediates EGF -driven mammary cell migration
  Nat Cell Biol. 2007, Vol 9, 961-974

• Yi-Chun Liao, Su Hao Lo
  Deleted in liver cancer-1 (DLC-1): A tumor suppressor not just for liver
  J Biocel. 2007

• Yi-Chun Liao, Lizhen Si, Ralph W. deVere White, Su Hao Lo
  The phosphotyrosine-independent interatcion of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1
  J Cell Biol. 2007, Vol 176, 43-49

• Lo, S. H.
  Focal adhesions: What's new inside
  Biol. 2006, 294:280-91

• You, Z., Shi, X. B., DuRaine, G., Haudenschild, D., Tepper, C. G., Lo, S. H., Gandour-Edwards, R., deVere While, R., Reddi, A. H.
  Interleukin-17 receptor-like gene is a novel anti-apoptotic gene highly expressed in androgen independent prostate cancer
  Cancer Res. 2006, 66:175-183

• Chen, N. T., and Lo, S. H
  The N-terminal half of talin2 is sufficient for mouse development and survive
  Biochem Biophys Res Commun. 2005, 337:670-676

• Lo, S. S., Lo, S. H., and Lo, S. H.
  Cleavage of cten by caspase 3 during apoptosis
  Oncogene. 2005, 24:4311-4314

• Chiang, M.K., Liao, Y.C., Kuwabara, Y, and Lo, S. H.
  Targeted disruption of tensin3 in mice results in growth retardation and postnatal lethality
  Dev. Biol. 2005, 279:368-377

• Cui, Y., Liao, Y. C., and Lo, S. H.
  Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3
  Molecular Cancer Research 2004 Apr;2(4):225-32.

• Lo, S.H.
  Molecules in focus: Tensin.
  Int. J. Biochem. Cell Biol. 2003

• Chen H, Lo SH.
  Regulation of tensin-promoted cell migration by its focal adhesion binding and Src homology domain 2.
  Biochem J. 2003 Mar 15;370(Pt 3):1039-45.

• Lo SH, Lo TB.
  Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer.
  Cancer Res. 2002 Aug 1;62(15):4217-21.

• Chen H, Duncan IC, Bozorgchami H, Lo SH.
  Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migration.
  Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):733-8.

• Vinall RL, Lo SH, Reddi AH.
  Regulation of articular chondrocyte phenotype by bone morphogenetic protein 7, interleukin 1, and cellular context is dependent on the cytoskeleton.
  Exp Cell Res. 2002 Jan 1;272(1):32-44.

• Ishii A, Lo SH.
  A role of tensin in skeletal-muscle regeneration.
  Biochem J. 2001 Jun 15;356(Pt 3):737-45.

• Chen H, Ishii A, Wong WK, Chen LB, Lo SH.
  Molecular characterization of human tensin.
  Biochem J. 2000 Oct 15;351 Pt 2:403-11.

• Tikoo A, Cutler H, Lo SH, Chen LB, Maruta H.
  Treatment of Ras-induced cancers by the F-actin cappers tensin and chaetoglobosin K, in combination with the caspase-1 inhibitor N1445.
  Cancer J Sci Am. 1999 Sep-Oct;5(5):293-300.