Other injectable medications for diabetes
Pramlintide (Symlin)
| Drug Name | Brand Name | Doses Available (mcg) |
|---|---|---|
| Pramlintide | Symlin | 15-120 |
This medication is a member of the synthetic amylin (neuroendocrine hormone) class.
How it works
- This medication is used with insulin to lower blood sugar, especially after meals by slowing down the rate in which food is digested
- Decreases glucose secretion by the liver
- Works to decrease appetite, some people may lose weight as a result
Guidelines for use
- In people with Type 1 diabetes using insulin
- In people with Type 2 diabetes who are taking insulin, Sulfonylurea and/or Metformin
What to do if a dose is forgotten
- Resume usual dose at next scheduled injection time
- Do not “double up” on Symlin
Side effects
Side effects may occur when starting this medication but will often lessen once your body is used to the medication
- Nausea, vomiting, diarrhea, headache
- May cause severe low blood sugars if pre-meal insulin dose not adjusted
Who should NOT take this medication
- People with Type 2 diabetes who are on not insulin
- People with digestive issues (gastroporesis)
Exenatide (Byetta)
| Drug Name | Brand Name | Doses Available (mcg) |
|---|---|---|
| Exenatide | Byetta | 5, 10 |
This medication is the member of incretin mimetic class.
How it works
- Increases glucose dependent insulin secretion
- Decreases output of sugar by the liver
- Decreases the rate sugar enters blood by delaying how the food is digested in the gut
- Decreases food intake by appetite suppression, some people may lose weight as a result
Guidelines for use
- Byetta is indicated as add-on therapy to improve blood sugar control in people with Type 2 diabetes who are taking Metformin, a Sulfonylurea, a Thiazolidinedione, or a combination of these medications
- Inject 30-60 minutes before breakfast and dinner
What to do if a dose is forgotten
- Resume usual dose at next scheduled injection time
- Do not “double up” on Byetta
Side effects
Side effects may occur when starting this medication but will often lessen once your body is used to the medication
- Nausea, vomiting, diarrhea, jitters, dizziness, headache
- If you arte taking a Sulfonylurea with Byetta, you may experience a low blood sugar
Who should NOT take this medication
- People with Type 1 diabetes or people with severe kidney problems or digestive issues (gastroporesis)

