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Research in pediatric endocrinology

Nicole Glaser, M.D.

Nicole Glaser's research has focused on pediatric diabetic ketoacidosis (DKA). Specifically she has been studying the cause and treatment of a serious complication of DKA, cerebral edema.  Both animal and human studies utilize magnetic resonance imaging technologies to assess brain metabolism, perfusion and edema formation. In addition, Nicole Glaser investigates methods for improving blood glucose control in children with diabetes.  This has included helping to develop an insulin dosage calculation device and a computer game.

Click here for Nicole Glaser's Community of Science CV.

Dennis Styne, M.D.

Dennis Styne conducts clinical research on childhood obesity. Using activity, education, and pharmaceutical therapy, he studies children in his Fit-Kid Weight Management Clinic, evaluating the best methods of assessment and treatment of obesity and its comorbidities. He also has an outreach program to Northern California Indian Rancherias that combines education for local health workers and telehealth communication between the UC Davis Medical Center-based children's weight management team and the families. Additional research involves improving therapies for disorders of pubertal development and growth.

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Craig Warden, Ph.D.

Craig Warden uses molecular genetics techniques in mouse models to study the impact of natural genetic variants on obesity and on response to diet and exercise. He has identified a protein that alters levels of hypothalamic alpha-melanocyte stimulating hormone (alpha-MSH) — a natural food intake inhibitor. This protein is a potential drug target because inhibitors decrease hunger. Craig Warden also studies whether some people are genetically programmed to fail to maintain weight loss following gastric bypass surgery.

Click here for Craig Warden's Community of Science CV.