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UC Davis Children’s Hospital

Francis R. Poulain, M.D.

Francis R. Poulain

Clinical/Research Interests

Dr. Poulain focuses his research on the biology of lung surfactant and its metabolism using a variety of biophysical and molecular techniques. He serves as a senior mentor to other researchers, advising them about laboratory methods, molecular biology techniques, grant writing, and design and implementation of studies.

Title:

Associate Professor
Director of Neonatal-Perinatal Training Program

Specialty:

Pediatric Neonatology

Center/Program Affiliation:

UC Davis Children's Hospital

Address:

UC Davis Medical Center
2315 Stockton Blvd., Suite NICU
Sacramento, CA 95817

Other Languages:

French

Education:

University of Medicine
Caen
France
M.D. 1975

Institut Notre-Dame
Avranches, Frances
B.S. 1969

Internships:

University of Utah
Salt Lake City, Utah
1985-1986
Pediatrics

Residency:

University of Utah
Salt Lake City, Utah
1986-1988
Pediatrics

Fellowships:

UC San Francisco
San Francisco, California
1988-1991
Neonatal-Perinatal Medicine

Board Certifications:

American Board of Pediatrics, 1999
American Board of Pediatrics, Neonatal-Perinatal Medicine, 1999

Professional Memberships:

American Academy of Pediatrics
American Academy of Pediatrics, Fellow
American Association for the Advancement of Science
American Thoracic Society
Society for Pediatric Research
Western Society for Pediatric Research

Select Recent Publications:

Haczku A, Cao Y, Vass G, Kierstein S, Nath P, Atochina-Vasserman EN, Scanlon ST, Li L, Griswold DE, Chung KF, Poulain FR, Hawgood S, Beers MF, and Crouch EC. IL-4 and IL-13 Form a Negative Feedback Circuit with Surfactant Protein-D in the Allergic Airway Response. J Immunol, 176(6):3557-3565.

Sorensen GL, Madsen J, Kejling K, Tornoe I, Nielsen O, Townsend P, Poulain F, Nielsen CH, Reid KB, Hawgood S, Falk E, Holmskov U. Surfactant protein D is proatherogenic in mice. Am J Physiol Heart Circ Physiol, Dec 30, [Epub ahead of print].

Atochina EN, Beers MF, Hawgood S, Poulain F, Davis C, Fusaro T, and Gow AJ. Surfactant Protein-D, a mediator of innate lung immunity, alters the products of NO metabolism. Am J Respir Cell Mol Biol, 30(3):271-279.

Atochina EN, Gow AJ, Beck JM, Haczka A, Inch A, Kadire H, Tomer Y, Davis C, Preston AM, Poulain F, Hawgood S, and Beers MF. Delayed clearance of pneumocystis carinii infection, increased inflammation, and altered nitric oxide metabolism in lungs of surfactant protein-D knockout mice. J Infect Dis, 189(8):1528-1539.

Hawgood S, Brown C, Edmondson J, Stumbaugh A, Allen L, Goerke J, Clark H, and Poulain F. Pulmonary collectins modulate strain-specific type A influenza infection and host responses. J Virol, Aug, 78(16):8565-8572.

Schaub B, Westlake RM, He H, Arestides R, Haley KJ, Campo M, Velasco G, Bellou A, Hawgood S, Poulain FR, Perkins DL, and Finn PW. Surfactant protein D deficiency influences allergic immune responses. Clin Exp Allergy, 34(12):1819-1826.

Jain D, Dodia C, Bates SR, Hawgood S, Poulain FR, and Fisher AB. SP-A is necessary for increased clearance of alveolar DPPC with hyperventilation or secretagogues. Am J Physiol Lung Cell Mol Physiol, 284(5):L759-L765.

Bengtsson BO, Wootton-Gorges SL, Poulain FR, and Sherman MP. Urinary effects of morphine in preterm infants. Acta Paediatr, 92(2):251-253.

Li G, Siddiqui Y, Hendry M, Akiyama J, Edmondson J, Brown C, Allen L, Levitt S, Poulain F, and Hawgood S. Surfactant Protein-A deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of Influenza A virus. Am J Respir Cell Mol Biol, 26(3):277-282.

Akiyama J, Hoffman A, Brown C, Allen L, Edmondson J, Poulain FR, and Hawgood S. Tissue distribution of surfactant proteins A and D in the mouse. J Histochem Cytochem, 50(7):993-996.

To see if Francis R. Poulain is accepting new patients, or for assistance finding a UC Davis doctor, please call (800) 2-UC DAVIS.