Clinical/Research Interests

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Select Recent Publications:

Potter E*, Cheng Y, Knight JB, Gordish H, Natale JE. Metallothionein I and II expression slows the microglial response to in vivo target deprivation. J Neurotrauma, 24(1):28-42, 2007. (*mentored student)

Natale JE*, Guerguerian A-M*, Joseph JG, McCarter R, Shao C, Slomine B, Christensen J, Johnston J, Shaffner DH. (*equal contributors). Randomized trial of magnesium sulfate infusion in children with severe traumatic brain injury: Feasibility and hemodynamic safety. Pediatric Critical Care Medicine, 8(1):1-9, 2007. (feature article)

Sohn J*, Natale J*, Chew L-J, Belachew S, Cheng Y, Aguirre A, Lytle J, Oumesmar B-N, Kerninon C, Kanai-Azuma M, Kanai Y, Gallo V. (*equal contributors). Identification of Sox17 as a transcription factor that regulated oligodendrocyte development. J Neurosci, 26:9722-9735, 2006.

Natale JE, Joseph JG, Pretzlaff R, Silber T, Guerguerian AM. Clinical trials in pediatric traumatic brain injury: Unique challenges and potential responses. Developmental Neurosci, 28:276-290, 2006.

Molon A, DiGiovanni S, Hathout Y, Natale J, Hoffman E. Functional recovery of glycine receptors in a spastic murine model of startle disease. Neurobiology of Disease, 21:291-304, 2006.

Sharangpani A, Natale J. Critical appraisal of: Wheeler DS, Jacobs BR, Kenreigh CA, Bean JA, Hudson TK, Brilli RJ, Sehgal M. Theophylline versus terbutaline in treating critically ill children with status asthmaticus: A prospective, randomized, controlled trial. Pediatr Crit Care Med, 6:142-147, 2005. In: The PedsCCM Evidence-Based Journal Club, Nov. 17, 2005. Available from: http://pedsccm.wustl.edu/EBJ/THERAPY/Wheeler-theophylline.html.

Howard I, Joseph JG, Natale JE. Pediatric traumatic brain injury: Are there racial/ethnic disparities in brain injury severity, mortality or medical disposition? Ethnicity & Disease, 15(suppl 5):S5-51-S5-56, 2005.

Natale J, Knight JB, Cheng Y, Rome J, Gallo V. Metallothionein I & II mitigate age-dependent secondary brain injury. J Neurosci Res, 78:303-314, 2004.

Cernak I, Vink R, Natale J, Stoica B, Lea P, Movsesyan V, Ahmed R, Knoblach S, Fricke ST, Faden A. The “dark side” of endocannabinoids: A neurotoxic role for anandamide. J Cereb Blood Flow Metab, 24:564-578, 2004.

Stockwell D, Natale JE. Critical appraisal of: Culbert EL, Ashburn DA, Cullen-Dean G, et al. Quality of life of children after repair of transposition of the great arteries. Circulation, 108:857-862, 2003. In: The PedsCCM Evidence-Based Journal Club, September 4, 2004. Available from: http://pedsccm.wustl.edu/EBJ/QUALITY/Culbert-QOL-TGV.html.