Department of Cell Biology and Human Anatomy
Department of Cell Biology and Human Anatomy
Our Team
Faculty
Kenneth A. Beck, Ph.D.
Thomas N. Blankenship, Ph.D.
Camie Chan, Ph.D.
Wenbin Deng, Ph.D.
Gordon Douglas, Ph.D.
Allen C. Enders, Ph.D.
Kent Erickson, Ph.D.
Paul FitzGerald, Ph.D.
Qizhi Gong, Ph.D.
Douglas S. Gross, M.D., Ph.D.
John Hess, Ph.D.
Paul Knoepfler, Ph.D.
Vijaya Kumari, M.B.B.S., Ph.D.
Ron Li, Ph.D.
Xiao-Bo Liu, Ph.D.
Stanley Meizel, Ph.D.
Paul Primakoff, Ph.D.
Alice F. Tarantal, Ph.D.
Richard P. Tucker, Ph.D.
Chenji Zhou, Ph.D.
Staff
Postdoctoral Fellows
Graduate Students
Qizhi Gong, Ph.D.
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Research Interests
Brain development is a finely orchestrated process. Transient abnormalities, such as delayed or excessive growth of axons and dendrites in neurons can have a prolonged impact in the formation of functional connections. Early postnatal stages are critical periods, in which both intrinsic genetic programs and sensory experience participate in the formation and refinement of functional circuitry. My lab uses mouse olfactory system as a model to study the molecular mechanisms of neuronal network formation and plasticity. Using a combination of cell biological, genetic and molecular biological approaches, we are focused on studying molecules that regulate olfactory sensory axon growth and guidance, mitral cell dendritic differentiation and olfactory circuitry formation.
Representative Publications
Cheng TW, and Gong Q (2009) Secreted TARSH regulates olfactory mitral cell dendritic complexity. Eur J Neurosci 29: 1083-1095.
Tran H. Chen H. Walz A. Posthumus J.C. and Gong Q. (2008) Influence of olfactory epithelium on mitral/tufted cell dendritic outgrowth. PLoS One 3(11): e3816 doi:10.1371/journal.pone.0003816.
Chen H. Dadsetan S. Fomina A.F. and Gong Q. (2008) Expressing exogenous functional odorant receptors in cultured olfactory sensory neurons. Neural Dev 3:22.
Lee W. Cheng T.W. and Gong Q. (2008) Olfactory sensory neuron specific and sexually dimorphic expression of protocadherin 20. J Comp Neurol 507(1): 1076-86.
Chen H. Kohno K. and Gong Q. (2005) Conditional ablation of mature olfactory sensory neurons mediated by diphtheria toxin receptor. J Neurocytology 34: 37-47.
Recent/Current Teaching
CHA 400, Developmental, Gross and Radiographic Anatomy
MCB 255, Molecular Mechanisms of Animal Development
CHA 298, Current Topics in Cell Biology
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