Lihong Qi
Assistant Professor
Department of Public Health Sciences
Division of Biostatistics
Rowe Program in Human Genetics
4458 Tupper Hall
Office: (520) 754-92344

2003 - 2005 — Post-Doctoral Research Fellow, Fred Hutchinson Cancer Research Center
2003 Ph.D. — Biostatistics, University of Washington
2000 M.S. — Biostatistics, University of Washington
1998 M.S. — Statistics, Florida State University
1996 M.S. — Applied Mathematics, Peking University, P.R. China
1993 B.S. — Computational Mathematics, Liaoning University, P.R. China

My research interests include design and analysis of genetic association studies for complex diseases, survival analysis, and modeling missing data and measurement error problems. As complete genome sequencing offers a comprehensive approach to test all human genetic variation for association to complex diseases, it is important to develop cost-efficient designs and novel analysis method for large-scale high-dimensional SNP association studies. We have employed multi-stage designs that use a pooled DNA approach in early stages, and proposed an odds ratio approach to relating SNP allele frequency to disease risk using pooled DNA, in conjunction with a simple empirical variance estimator. The proposed design and analysis methods can allow high-throughput genome-wide SNP association studies to be conducted at affordable costs, with reasonable sensitivity and few false positives. Currently, I am also interested in methods for admixture mapping, gene and gene and gene and environment interactions.

Ross Prentice, Lihong Qi. (2006) "Aspects of the Design and Analysis of High-Dimensional SNP Studies for Disease Risk Estimation". Biostatistics, in press.

Denise E. Bonds, Norman Lasser, Lihong Qi, Robert Brzyski, Bette Caan, Gerardo Heiss, Marian Limacher, James H. Liu, Ellen Mason, Albert Oberman, Mary Jo O'Sullivan, Lawrence S. Phillips, Ron Prineas, Lesley Tinker. (2006) "The Effect of Conjugated Equine Estrogen Alone on Diabetes Incidence: The Results of the Women's Health Initiative". Diabetologia, in press.

Lihong Qi, C.Y. Wang, Ross L. Prentice. (2005) "Weighted Estimators for Proportional Hazards Model with Missing Covariates". Journal of the American Statistical Association, 100, 1250-1263.

Yinjie Tang, Lihong Qi, Barbara Krieger-Brockett. (2005) "Factors That Influence Microbial Phenanthrene Biodegradation Rates: Regression With Categorical Variables". Chemosphere, 59, 729-741.