George A. Kaysen, M.D., Ph.D.

Professor and Acting Chair

6311 Genome Building
or 4303 Tupper Hall
Ph: (530) 752-7271, (530) 752-2970 (Genome)
gakaysen@ucdavis.edu

• Roles of nutrition and inflammation in establishing plasma protein composition and body composition in humans. Albumin metabolism in nephrotic syndrome; regulation of hepatic gene express.
• Mechanism of hyperlipidemia in renal disease, consequence and cause of inflammation in dialysis, effects of inflammation on vascular endothelial structure and function, regulation of plasma protein composition.

Molecular, Cellular and Integrative Physiology

1. Kaysen GA, Levin NW, Mitch WE, Chapman AL, Kubala L, Eiserich JP.
   Evidence that C-Reactive Protein or IL-6 Are Not Surrogates for All Inflammatory Cardiovascular  Risk Factors in Hemodialysis Patients.
   Blood Purif. 2006 Oct 23;24(5-6):508-516 [Epub ahead of print]
    
2. Kaysen GA, Muller HG, Ding J, Chertow GM.
   Challenging the validity of the EPO index.
   Am J Kidney Dis. 2006 Jan;47(1):166.
    
3. Kaysen GA.
   Association between inflammation and malnutrition as risk factors of cardiovascular disease.
   Blood Purif. 2006;24(1):51-5. Review.
    
4. Don BR, Spin G, Nestorov I, Hutmacher M, Rose A, Kaysen GA.
   The pharmacokinetics of etanercept in patients with end-stage renal disease on haemodialysis.
   J Pharm Pharmacol. 2005 Nov;57(11):1407-13.
    
5. Kaysen GA.
   Effects of inflammation on plasma composition and endothelial structure and function.
   J Ren Nutr. 2005 Jan;15(1):94-8.
    
6. Kaysen GA.
   Inflammation: cause of vascular disease and malnutrition in dialysis patients.
   Semin Nephrol. 2004 Sep;24(5):431-6. Review.
    
7. Kaysen GA, Dubin JA, Muller HG, Rosales L, Levin NW, Mitch WE; HEMO Study Group NIDDK.
   Inflammation and reduced albumin synthesis associated with stable decline in serum albumin in hemodialysis patients.  
   Kidney Int. 2004 Apr;65(4):1408-15.
    
8. Kaysen GA, Muller HG, Young BS, Leng X, Chertow GM.
   The influence of patient- and facility-specific factors on nutritional status and survival in hemodialysis.
   J Ren Nutr. 2004 Apr;14(2):72-81.
    
9. Kaysen GA, Eiserich JP.
   The role of oxidative stress-altered lipoprotein structure and function and microinflammation on cardiovascular risk in patients with minor renal dysfunction.
   J Am Soc Nephrol. 2004 Mar;15(3):538-48. Review.
    
10. Kaysen GA, Eiserich JP.
    Characteristics and effects of inflammation in end-stage renal disease.
    Semin Dial. 2003 Nov-Dec;16(6):438-46. Review.
     
11. Kaysen GA.
    Serum albumin concentration in dialysis patients: why does it remain resistant to therapy?
    Kidney Int Suppl. 2003 Nov;(87):S92-8. Review.
     
12. Kaysen GA, Kumar V.
    Inflammation in ESRD: causes and potential consequences.
    J Ren Nutr. 2003 Apr;13(2):158-60. Review.
     
13. Kaysen GA, Dubin JA, Muller HG, Mitch WE, Rosales L, Levin NW; HEMO Group.
    Impact of albumin synthesis rate and the acute phase response in the dual regulation of fibrinogen levels in hemodialysis patients.
    Kidney Int. 2003 Jan;63(1):315-22.