Department of Biochemistry and Molecular Medicine

Department of Biochemistry and Molecular Medicine

Su Hao Lo, Ph.D.

 

Su Hao Lo, Ph.D.

Professor
Research I Room 3002
(916) 734-3656
e-mail

Recent/Current
Research Funding

National Institutes of Health

Graduate Group Affiliations

Biochemistry, Molecular, Cellular and Developmental Biology 

Pharmacology and Toxicology

Comparative Pathology

Laboratory Personnel

Dr. Irene (Yi-Ping) Shih

Dr. Shiao-Ya Hong

Dr. Aifeng Wang

Dr Sun, Peng

Yeh, Sandy (Yu-Jung)

Research Interests

 

Signal transduction mediated through focal adhesions and their roles in tissue and disease development

 

Representative Publications

Liao, Y. C., Chen, N. T., Shih Y. P., Dong, Y., Lo, S. H. Up-regulation of C-terminal tensin-like molecule promotes the tumorigenicity of colon cancer cells through b-catenin. Cancer Res 2009, 69:4563- 4566.

Lin, Y., Chen, N. T., Shih, Y. P., Liao, Y. C., Xue, L., and Lo, S. H, DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration. Oncogene 2010, 29:3010-3016

Shih, Y.P., Liao, YC., Lin, Y., Lo, S. H. DLC1 negatively regulates angiogenesis in a paracrine fashion. Cancer Res 2010, 70:8270-8275.

Shih Y.P., Takada, Y., Lo, S.H. Silencing of DLC1 promotes PAI-1 expression and reduces normal cell migration. Mol Cancer Res. 2012, 10:34-39.

Li, J.R., Shi, L., Deng, Z., Lo, S. H., Liu, G.Y. Nanostructures of Designed Geometry and Functionality Enable Regulation of Cellular Signaling Processes. Biochemistry 2012, 51, 5876–5893

2012 Shi L, Li, J.R., Shih, Y.P., Lo, S. H., Liu, G. Y., Nanogratings of Fibronectin Provide an Effective Biochemical Cue for Regulating Focal Adhesion and Cellular Structure. Nano Res (2012 In press)

 

Recent/Current Teaching

Upper division courses

  • 192 Internship in Biological Chemistry
  • 198 Group Study
  • 199 Special Study for Advanced Undergraduates

Graduate courses

  • 209 Prostaglandins/Leukotrienes and Related Lipids (offered even years)
  • 214 Molecular Medicine
  • 217 Molecular Genetics of Fungi (odd years)
  • 222 Mechanisms of Translational Control (even years)
  • 230 Practical NMR
  • 231 Biomedical NMR (same as BPH 231)
  • 291 Human Genetics Seminar
  • 298 Group Study
  • 299 Research

Professional courses for medical students

  • 410A Molecular and Cell Biology
  • 410B Cell Biology and Metabolism
  • 414 Molecular Medicine
  • 491 Human Genetics Seminar
  • 497 Tutoring in Biological Chemistry
  • 498 Group Study
  • 499 Research