Clinical/Research Interests:

I provide general and cardiac anesthesia.  I have been engaged in basic and clinical research for more than 20 years.  My primary research areas include myocardial ischemia/reperfusion injury, pre- & post-conditioning in myocardial protection and high-risk surgery outcomes.

Title:

Associate Professor
Director, Clinical Anesthesia Research

Specialty:

Center/Program Affiliation:

Address:

Phone:

Other Languages:

Education:

Nanjing Medical College
Jiangsu
China
M.D. 1987

Suzhou Medical College
Suzhou
China
1982

Internships:

Residency:

Fellowship:

Board Certifications:

National Board of Echocardiography, Perioperative Transesophageal Echocardiography, 2004
American Board of Anesthesiology , 2001
Medical Board of California, 1998

Professional
Memberships:

Select Recent
Publications:

Ong L, Liu H.  Current status in management of ventilator-associated pneumonia.  J Clin Anesthesiol, 28(8):824-9.

Kumar S, Young JN, Liu H. Atrial septal aneurysm causing impaired venous drainage in CPB. Ann Thoracic Surg, 2012.

Konia M, Liu H. Recombinant activated Factor VII in cardiac surgery: the new magic drug in post-aprotinin era. J Clin Anesthesiol, 2012 January, 28(1): 103-6.

Soares JHN, Brosnan RJ, Fukushima FB, Hodges J, Liu H. Solubility of haloether anesthetics in human and animal blood. Anesthesiology, 2012 Jul;117(1):48-55.

Cao L, Young JN, Liu H, Silvestry S, Sun W, Zhao N, Dielh J, Sun JZ. Preoperative aspirin use and outcomes in cardiac surgery patients. Ann Surg, 2012 February, 255(2): 399-404.

Xie H, Wang C, Wu X, Liu X, Qiao S, Liu C, Liu H. Parthenolide attenuates LPS-induced activation of NF-κΒ in a time-dependent manner in rat myocardium. Journal of Biomedical Research, 2012 26(1): 37-43.

Liu H. Is the PAC Passe: Exposing the data for continued (mis)use in perioperative and critical care settings. J Clin Anesth, 2011 27(6): 627-31.

Zhong C, Fleming NW, Lu X, Moore PG, Liu H. Age-associated differences in gene expression in response to delayed anesthetic preconditioning. Age, 2011 October 19 [Epub ahead of print].

Tang D, Liu H. Acute left atrial intramural wall dissection after mitral valve replacement. Journal of Cardiothoracic and Vascular Anesthesia, 2011 25, 3(June): 498-500.

Sun JZ, Cao LH, Liu H. ACE inhibitors in cardiac surgery: current studies and controversies. Hypertension Research, 2011 34: 15-22.

Lu X, Moore PG, Liu H, Schaefer S. Phosphorylation of ARC is a critical element in the antiapoptotic effect of anesthetic preconditioning. Anesth Analg, 2011 112(3): 525-31.

Liu H, Moore PG. KΑΤΡ channel blocker does not abolish the protective effect of NHE1 inhibition against ischaemia/reperfusion in aged myocardium. Eur J Anaesthesiol, 2010 August, 27(8):740-6.

Liu H, Cala PM, Anderson SE. Na/H exchange inhibition protects newborn heart from ischemia/reperfusion injury by limiting Na+-dependent Ca2+ overload. J Cardiovasc Pharmacol, 2010 55(3): 227-33.

Lu X, Liu H, Wang L, Schaefer S. Activation of NF-κΒ is a critical element in the antiapoptotic effect of anesthetic preconditioning. Am J Physiol Heart Circ Physiol, 2009 May, 296:H1296-304.

Konia MR, Schaefer S, Liu H. Nuclear factor-κΒ inhibition provides additional protection against ischaemia/reperfusion injury in delayed sevoflurane preconditioning. Eur J of Anaesthesiol, 2009 26(6): 496-503.

Deyhimy DI, Fleming NW, Brodkin IG, Liu H. Anesthetic preconditioning combined with post conditioning offers no additional benefit over preconditioning or postconditioning alone. Anesth Analg, August, 2007 105(2): 316-24.

Lutz M, Liu H. Inhaled sevoflurane produces better delayed myocardial protection at 48 versus 24 hours after exposure. Anesth Analg, 2006 102: 984-90.

Anderson SE, Liu H, Beyschau A, Cala PM. Effects of cold cardioplegia on pH, Na, and Ca in newborn rabbit hearts. Am J Physiol Heart Circ Physiol, 2006 290: H1090-7.

Liu H, Wang L, Schaefer S. Sevoflurane preconditioning limits intracellular/mitochondrial Ca2+ in ischemic newborn myocardium. Anesthesia and Analgesia, 2005 101(2): 349-55.

Zhong C, Zhou Y, Liu H. Nuclear factor kB and anesthetic preconditioning during myocardial ischemia-reperfusion. Anesthesiology, 2004 100: 540-6.