Clinical/Research Interests:


I provide general and cardiac anesthesia.  I have been engaged in basic and clinical research for more than 20 years.  My primary research areas include myocardial ischemia/reperfusion injury, pre- & post-conditioning in myocardial protection and high-risk surgery outcomes.


Director, Clinical Anesthesia Research


Cardiovascular and Thoracic Anesthesiology

Center/Program Affiliation:



Patient Support Services Building
4150 V St., Suite 1200
Sacramento, CA  95817


(916) 734-5031

Other Languages:



Nanjing Medical College
M.D. 1987

Suzhou Medical College


St. Vincent Hospital and Medical Center
New York, New York


UC Davis Medical Center
Sacramento, California
Anesthesiology and Pain Medicine


UC Davis Medical Center
Sacramento, California
Adult, Cardiothoracic Anesthesiology

Board Certifications:

National Board of Echocardiography, Perioperative Transesophageal Echocardiography, 2004
American Board of Anesthesiology , 2001
Medical Board of California, 1998


American Medical Association
American Society of Anesthesiologists
California Society of Anesthesiologists
Chinese American Medical Association of California
Chinese American Society of Anesthesiology
International Anesthesia Research Society
Society of Cardiovascular Anesthesiologists

Select Recent

Ong L, Liu H.  Current status in management of ventilator-associated pneumonia.  J Clin Anesthesiol, 28(8):824-9.

Kumar S, Young JN, Liu H. Atrial septal aneurysm causing impaired venous drainage in CPB. Ann Thoracic Surg, 2012.

Konia M, Liu H. Recombinant activated Factor VII in cardiac surgery: the new magic drug in post-aprotinin era. J Clin Anesthesiol, 2012 January, 28(1): 103-6.

Soares JHN, Brosnan RJ, Fukushima FB, Hodges J, Liu H. Solubility of haloether anesthetics in human and animal blood. Anesthesiology, 2012 Jul;117(1):48-55.

Cao L, Young JN, Liu H, Silvestry S, Sun W, Zhao N, Dielh J, Sun JZ. Preoperative aspirin use and outcomes in cardiac surgery patients. Ann Surg, 2012 February, 255(2): 399-404.

Xie H, Wang C, Wu X, Liu X, Qiao S, Liu C, Liu H. Parthenolide attenuates LPS-induced activation of NF-κΒ in a time-dependent manner in rat myocardium. Journal of Biomedical Research, 2012 26(1): 37-43.

Liu H. Is the PAC Passe: Exposing the data for continued (mis)use in perioperative and critical care settings. J Clin Anesth, 2011 27(6): 627-31.

Zhong C, Fleming NW, Lu X, Moore PG, Liu H. Age-associated differences in gene expression in response to delayed anesthetic preconditioning. Age, 2011 October 19 [Epub ahead of print].

Tang D, Liu H. Acute left atrial intramural wall dissection after mitral valve replacement. Journal of Cardiothoracic and Vascular Anesthesia, 2011 25, 3(June): 498-500.

Sun JZ, Cao LH, Liu H. ACE inhibitors in cardiac surgery: current studies and controversies. Hypertension Research, 2011 34: 15-22.

Lu X, Moore PG, Liu H, Schaefer S. Phosphorylation of ARC is a critical element in the antiapoptotic effect of anesthetic preconditioning. Anesth Analg, 2011 112(3): 525-31.

Liu H, Moore PG. KΑΤΡ channel blocker does not abolish the protective effect of NHE1 inhibition against ischaemia/reperfusion in aged myocardium. Eur J Anaesthesiol, 2010 August, 27(8):740-6.

Liu H, Cala PM, Anderson SE. Na/H exchange inhibition protects newborn heart from ischemia/reperfusion injury by limiting Na+-dependent Ca2+ overload. J Cardiovasc Pharmacol, 2010 55(3): 227-33.

Lu X, Liu H, Wang L, Schaefer S. Activation of NF-κΒ is a critical element in the antiapoptotic effect of anesthetic preconditioning. Am J Physiol Heart Circ Physiol, 2009 May, 296:H1296-304.

Konia MR, Schaefer S, Liu H. Nuclear factor-κΒ inhibition provides additional protection against ischaemia/reperfusion injury in delayed sevoflurane preconditioning. Eur J of Anaesthesiol, 2009 26(6): 496-503.

Deyhimy DI, Fleming NW, Brodkin IG, Liu H. Anesthetic preconditioning combined with post conditioning offers no additional benefit over preconditioning or postconditioning alone. Anesth Analg, August, 2007 105(2): 316-24.

Lutz M, Liu H. Inhaled sevoflurane produces better delayed myocardial protection at 48 versus 24 hours after exposure. Anesth Analg, 2006 102: 984-90.

Anderson SE, Liu H, Beyschau A, Cala PM. Effects of cold cardioplegia on pH, Na, and Ca in newborn rabbit hearts. Am J Physiol Heart Circ Physiol, 2006 290: H1090-7.

Liu H, Wang L, Schaefer S. Sevoflurane preconditioning limits intracellular/mitochondrial Ca2+ in ischemic newborn myocardium. Anesthesia and Analgesia, 2005 101(2): 349-55.

Zhong C, Zhou Y, Liu H. Nuclear factor kB and anesthetic preconditioning during myocardial ischemia-reperfusion. Anesthesiology, 2004 100: 540-6.